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These factors aid in building muscle and are synergistic with tension and progressive overload. These factors also help explain why Kaatsu (occlusion) training is highly effective at inducing hypertrophy despite the lower levels of muscle tension, at least when compared to traditional resistance training. This part will be a bit sciencey, but stick with me. Mechanical tension and metabolic stress are interrelated and signal hypertrophic responses through multiple pathways. For example, a high magnitude of active tension at longer muscle lengths creates the greatest hypertrophy effect. In other words, tension has the greatest effect when muscle is stretched while being activated. High tension through a full ROM is very effective at producing metabolic stress due to the prolonged muscle contractions that occludes the veins, which leaves no time for blood to escape the muscles and ultimately causes the pump effect. 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