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Also, it is not possible to know whether a patient is actually using a steroid to improve his or her condition (and, conversely, is using it to improve his or her condition). Some drugs may have the opposite effect; for example, some antihistamines may be beneficial because they reduce fever or itching while in excess they lead to weight gain or severe acne, prednisone for weight loss. The test does nothing to determine whether this is the case. However, certain medications, such as some antidepressants known to affect the levels of sex steroids, may cause significant weight gain if they are taken with this test. The test should also be used with some caution when considering whether an individual is likely to use anabolic steroids frequently for short periods of time or regularly.
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