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Androgenic steroids have high levels of the 5a-reductase enzyme present, which is responsible for converting testosterone into DHT (dihydrotestosterone)before being released for conversion into estrogen. This enzyme then has the opposite effect on the body to testosterone, and is the primary enzyme responsible for converting the adrenal cortex of the pituitary in females to estrogen/steroid hormones in the testes which are released in men. One study done on rats showed that testosterone therapy, in doses that exceed those found in human therapy, decreases the amount of 5a-reductase enzyme present, peptides bodybuilding cutting. Treatment with testosterone (or estrogen) reduces the activity of dopamine receptor (DRD3) and thereby increases the activity of catecholamine-transporting proteins (ATPases). This increases the release of catecholamines, which increases catecholamine levels.
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