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[2] Transdermal testosterone does not appear to have a negative effect on body composition per se, despite some studies failing to find that it is more effective than placebo. Despite muscle mass being increased, the increase is not large enough to affect muscle endurance, although other mechanisms may be involved in increasing muscle mass, such as growth factors (which are increased by insulin, increased protein synthesis, and increased synthesis of phosphatidylserine) and exercise, nolvadex prix tunisie. [29] After three weeks of supplementation, there were only statistically significant changes (increase in the muscle fascicles and collagen content and downregulation of myostatin in muscles) of a p less than. 01, which was similar to the changes seen following oral supplementation. [2] Some investigators report that testosterone supplementation in obese men can enhance a variety of factors, although these effects are modest.
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