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Capacitatea de a conduce vehicule sau de a folosi utilaje. Nu exista dovezi privind efecte ale produsului asupra atentiei si a timpului de reactie ale pacientilor. Doze si mod de administrare. Pentru dizolvarea calculilor biliari cu continut de colesterol, doza este de 300-600 mg pe zi (dupa sau in timpul meselor) coreaspunzator la 2-4 comprimate de Ursochol a 150 mg sau 1-2 comprimate Ursochol a. Pentru a mentine conditiile favorabile pentru dizolvarea calculilor biliari existenti, tratamentul trebuie sa dureze cel putin 4-6 luni pana la 12 luni sau mai mult, in functie de dimensiunea calculilor si evolutia sub tratament. Pentru tratamentul de mentinere sunt suficiente doze de 150 mg de 2 ori pe zi sau de 300 mg o data pe zi. In sindroamele dispeptice biliare, doza este de 1 comprimat a 150 mg de 2 ori pe zi. In hepatopatii cronice cu colestaza doza poate fi crescuta pana la 300 mg de 2-3 ori pe zi. Durata tratamentului trebuie hotarata de medic in functie atat de tipul si severitatea afectiunii cat si de raspunsul terapeutic. Dozele pot fi modificate de medic. Calculii biliari se pot calcifica in timpul tratamentului cu Ursochol. Ocazional, poate sa apara urticarie si in cazuri rare materiile fecale pot deveni pastoase. Comparativ cu acidul chenodezoxicholic, reactiile adverse ale UDCA difera considerabil ca frecventa si consecinte. Diareea este mai rara si dispare, de regula, spontan. Pruritul (mai ales in faza initiala a terapiei) poate aparea exceptional. Ocazional, in timpul tratamentului stadiilor avansate ale cirozei biliare primitive s-a observat decompensarea cirozei, aceasta reducandu-se dupa intreruperea tratamentului, klomen 50 mg fiyat 2021. In cazuri izolate, in timpul tratamentului cirozelor biliare primitive pot sa apara dureri severe in hipocondrul drept. Cresterea transaminazelor este nesemnificativa sau poate sa nu apara. Nivelul de colesterol ramane neschimbat. Nu au fost raportate cazuri de administrare a unor doze mai mari de 4 g pe zi. In cazul ingestiei accidentale de AUDC in doze mult mai mari, se recomanda a se aplica procedurile de dezintoxicare si de a se administra colestiramina (un agent chelator al acizilor biliari). A nu se utiliza dupa data de expirare inscrisa pe ambalaj. A se pastra la temperaturi sub 25?C, in ambalajul original. A nu se lasa la indemana si vederea copiilor. Cutie cu un blister transparent din PVC/Al a 10 comprimate.
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