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Scientific research has definitively established that increased testosterone levels lead to increased lean body mass, but it can also cause increases in aggression and irritability, at least in individuals who are predisposed to this type of behavior ( 30 ). These adverse effects are not seen with controlled doses of (pure) testosterone over short periods of time, however’generally they occur with very high doses taken for long periods of time, and the connection between high doses of pharmacological grade testosterone with supplemental testosterone boosters is far from clear. The precise dose of a testosterone booster for maximum efficacy is obviously going to depend on the specific formulation. With the most common ingredients, like vitamin D, magnesium, and zinc, the effective dose can be roughly compared to the recommended daily intake for that vitamin or mineral. When it comes to herbal compounds, the picture is less clear. Still, the top-rated testosterone boosters closely match the effective doses of ingredients like fenugreek seed and citrulline malate from scientific studies. For these compounds, following the supplement guidelines is the best policy, but you might need to take less if you have other supplements in your diet, like a male enhancement pill or a weight loss pill , that use the same ingredients. Some compounds, like fenugreek seed, can do double-duty as a weight loss aid and testosterone booster, so be on the lookout for accidentally taking too great of a dosage due to other supplements you are taking, even if they are for a completely different purpose. Q: What is the best testosterone booster for muscle growth? A: Testosterone has broad, systemic effects, but if you are specifically looking to increase muscle growth, there are a few less-common ingredients you should be on the lookout for. 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