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Several factors act on cells and tissues in concert, including hormone concentrations, the presence or absence of nutrients (metabolic equivalents of glucose), and the activity of enzymes within the liver. The levels of circulating insulin and FFAs appear to be closely related to insulin sensitivity, peptide fat loss before and after. Furthermore, increased concentrations of hormone (insulin, FFAs) increases the amount of circulating FFAs and results in the release of FFAs out of liver, into blood from muscles, or out of adipose tissue.
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