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For example, many who supplement will not have a problem with acne, but those who are genetically sensitive may find they have a problem. It should also be noted; 5-alpha reductase inhibitors will not affect this steroids androgenicity. It is the 5-alpha reductase enzyme that causes testosterone to reduce to DHT, but in this case there is nothing to inhibit as Oxymetholone is already a DHT compound. The androgenic nature of Anadrol causes this steroid to be a poor choice for women. The use of Oxymetholone will lead to severe virilization symptoms such as body hair growth, a deepening of the vocal chords and clitoral enlargement. Many often find it to also have a reducing effect on breast size and to promote menstrual irregularity. While women can safely supplement with some anabolic steroids, this is not one of them. Women should choose steroids with a weakened androgenic nature. 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